Cas9 & gRNA Delivery

Find the best Cas9 and gRNA delivery options for your genome engineering application—choose from mRNA, lentivectors, protein, AAV, and more

With a wealth of options for delivering Cas9 and gRNA, SBI supports a full range of genome engineering applications. Deliver Cas9 and gRNA via mRNA, lentivector, or AAV, or use purified Cas9 protein, and then choose from our all-in-one systems that deliver Cas9 and gRNA on a single vector or two-component systems for separate introduction of Cas9 and gRNA.

Not sure which system to choose? Take a look at our table below, or contact technical support—we’re here to help you find the right product for your application and can provide expert experimental support.

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Cas9 & gRNA Delivery Products

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EF1α-hsaCas9-U6-gRNA(SA) All-in-one AAV Cas9 SmartNuclease™ Plasmid

Extend genome editing capabilities to cutting edge in vivo applications with our All-in-one AAV Cas9 SmartNuclease Plasmid EF1α-hsaCas9-U6-gRNA(SA).
Size:
array(1) { [0]=> array(24) { ["attributes"]=> array(1) { ["attribute_size"]=> string(12) "10 Reactions" } ["availability_html"]=> string(0) "" ["backorders_allowed"]=> bool(false) ["dimensions"]=> array(3) { ["length"]=> string(0) "" ["width"]=> string(0) "" ["height"]=> string(0) "" } ["dimensions_html"]=> string(3) "N/A" ["display_price"]=> float(695) ["display_regular_price"]=> float(695) ["image"]=> array(18) { ["title"]=> string(32) "aav-ef1-alpha-hsacas9-u6-grna-sa" ["caption"]=> string(0) "" ["url"]=> string(97) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/aav-ef1-alpha-hsacas9-u6-grna-sa.png" ["alt"]=> string(0) "" ["src"]=> string(97) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/aav-ef1-alpha-hsacas9-u6-grna-sa.png" ["srcset"]=> string(326) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/aav-ef1-alpha-hsacas9-u6-grna-sa.png 345w, https://systembio.com/wp-content/uploads/crispr-cas9-systems/aav-ef1-alpha-hsacas9-u6-grna-sa-300x300.png 300w, https://systembio.com/wp-content/uploads/crispr-cas9-systems/aav-ef1-alpha-hsacas9-u6-grna-sa-100x100.png 100w" ["sizes"]=> string(31) "(max-width: 345px) 100vw, 345px" ["full_src"]=> string(97) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/aav-ef1-alpha-hsacas9-u6-grna-sa.png" ["full_src_w"]=> int(345) ["full_src_h"]=> int(345) ["gallery_thumbnail_src"]=> string(105) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/aav-ef1-alpha-hsacas9-u6-grna-sa-100x100.png" ["gallery_thumbnail_src_w"]=> int(100) ["gallery_thumbnail_src_h"]=> int(100) ["thumb_src"]=> string(105) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/aav-ef1-alpha-hsacas9-u6-grna-sa-300x300.png" ["thumb_src_w"]=> int(300) ["thumb_src_h"]=> int(300) ["src_w"]=> int(345) ["src_h"]=> int(345) } ["image_id"]=> string(4) "7251" ["is_downloadable"]=> bool(false) ["is_in_stock"]=> bool(true) ["is_purchasable"]=> bool(true) ["is_sold_individually"]=> string(2) "no" ["is_virtual"]=> bool(false) ["max_qty"]=> string(0) "" ["min_qty"]=> int(1) ["price_html"]=> string(142) "$695" ["sku"]=> string(13) "CASAAV100PA-1" ["variation_description"]=> string(83) "

Linearized all-in-one SmartNuclease AAV Plasmid (EF1α-hsaCas9-U6-gRNA(SA))

" ["variation_id"]=> int(63378) ["variation_is_active"]=> bool(true) ["variation_is_visible"]=> bool(true) ["weight"]=> string(0) "" ["weight_html"]=> string(3) "N/A" } }
(Cat. # CASAAV100PA-1)

EF1α-hsaCas9 Two Vector AAV Cas9 SmartNuclease™ Expression Plasmid

Extend genome editing capabilities to cutting edge in vivo applications with our Two Vector AAV Cas9 SmartNuclease Expression Plasmid EF1α-hsaCas9.
Size:
array(1) { [0]=> array(24) { ["attributes"]=> array(1) { ["attribute_size"]=> string(6) "10 µg" } ["availability_html"]=> string(0) "" ["backorders_allowed"]=> bool(false) ["dimensions"]=> array(3) { ["length"]=> string(0) "" ["width"]=> string(0) "" ["height"]=> string(0) "" } ["dimensions_html"]=> string(3) "N/A" ["display_price"]=> float(595) ["display_regular_price"]=> float(595) ["image"]=> array(18) { ["title"]=> string(37) "two-vector-system-aav-cas9-expression" ["caption"]=> string(0) "" ["url"]=> string(102) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-cas9-expression.png" ["alt"]=> string(0) "" ["src"]=> string(110) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-cas9-expression-600x522.png" ["srcset"]=> string(225) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-cas9-expression-600x522.png 600w, https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-cas9-expression.png 1188w" ["sizes"]=> string(31) "(max-width: 600px) 100vw, 600px" ["full_src"]=> string(102) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-cas9-expression.png" ["full_src_w"]=> int(1188) ["full_src_h"]=> int(1034) ["gallery_thumbnail_src"]=> string(110) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-cas9-expression-100x100.png" ["gallery_thumbnail_src_w"]=> int(100) ["gallery_thumbnail_src_h"]=> int(100) ["thumb_src"]=> string(110) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-cas9-expression-300x300.png" ["thumb_src_w"]=> int(300) ["thumb_src_h"]=> int(300) ["src_w"]=> int(600) ["src_h"]=> int(522) } ["image_id"]=> string(4) "7621" ["is_downloadable"]=> bool(false) ["is_in_stock"]=> bool(true) ["is_purchasable"]=> bool(true) ["is_sold_individually"]=> string(2) "no" ["is_virtual"]=> bool(false) ["max_qty"]=> string(0) "" ["min_qty"]=> int(1) ["price_html"]=> string(142) "$595" ["sku"]=> string(13) "CASAAV200PA-1" ["variation_description"]=> string(102) "

Cas9 expression vector for the Two Vector AAV SmartNuclease System (EF1α-hsaCas9 AAV Plasmid)

" ["variation_id"]=> int(63380) ["variation_is_active"]=> bool(true) ["variation_is_visible"]=> bool(true) ["weight"]=> string(0) "" ["weight_html"]=> string(3) "N/A" } }
(Cat. # CASAAV200PA-1)

EF1α-RFP-U6-gRNA(SA) Two Vector AAV Cas9 SmartNuclease™ gRNA Expression Plasmid

Extend genome editing capabilities to cutting edge in vivo applications with our Two Vector AAV Cas9 SmartNuclease gRNA Expression Plasmid EF1α-RFP-U6-gRNA(SA).
Size:
array(1) { [0]=> array(24) { ["attributes"]=> array(1) { ["attribute_size"]=> string(12) "10 Reactions" } ["availability_html"]=> string(0) "" ["backorders_allowed"]=> bool(false) ["dimensions"]=> array(3) { ["length"]=> string(0) "" ["width"]=> string(0) "" ["height"]=> string(0) "" } ["dimensions_html"]=> string(3) "N/A" ["display_price"]=> float(595) ["display_regular_price"]=> float(595) ["image"]=> array(18) { ["title"]=> string(37) "two-vector-system-aav-grna-expression" ["caption"]=> string(0) "" ["url"]=> string(102) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-grna-expression.png" ["alt"]=> string(0) "" ["src"]=> string(110) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-grna-expression-600x522.png" ["srcset"]=> string(225) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-grna-expression-600x522.png 600w, https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-grna-expression.png 1188w" ["sizes"]=> string(31) "(max-width: 600px) 100vw, 600px" ["full_src"]=> string(102) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-grna-expression.png" ["full_src_w"]=> int(1188) ["full_src_h"]=> int(1034) ["gallery_thumbnail_src"]=> string(110) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-grna-expression-100x100.png" ["gallery_thumbnail_src_w"]=> int(100) ["gallery_thumbnail_src_h"]=> int(100) ["thumb_src"]=> string(110) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/two-vector-system-aav-grna-expression-300x300.png" ["thumb_src_w"]=> int(300) ["thumb_src_h"]=> int(300) ["src_w"]=> int(600) ["src_h"]=> int(522) } ["image_id"]=> string(4) "7277" ["is_downloadable"]=> bool(false) ["is_in_stock"]=> bool(true) ["is_purchasable"]=> bool(true) ["is_sold_individually"]=> string(2) "no" ["is_virtual"]=> bool(false) ["max_qty"]=> string(0) "" ["min_qty"]=> int(1) ["price_html"]=> string(142) "$595" ["sku"]=> string(13) "CASAAV300PA-1" ["variation_description"]=> string(122) "

gRNA expression vector for the Two Vector AAV SmartNuclease System, linearized AAV plasmid (EF1α-RFP-U6-gRNA(SA))

" ["variation_id"]=> int(63382) ["variation_is_active"]=> bool(true) ["variation_is_visible"]=> bool(true) ["weight"]=> string(0) "" ["weight_html"]=> string(3) "N/A" } }
(Cat. # CASAAV300PA-1)

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