Cas9 & gRNA Delivery

Find the best Cas9 and gRNA delivery options for your genome engineering application—choose from mRNA, lentivectors, protein, AAV, and more

With a wealth of options for delivering Cas9 and gRNA, SBI supports a full range of genome engineering applications. Deliver Cas9 and gRNA via mRNA, lentivector, or AAV, or use purified Cas9 protein, and then choose from our all-in-one systems that deliver Cas9 and gRNA on a single vector or two-component systems for separate introduction of Cas9 and gRNA.

Not sure which system to choose? Take a look at our table below, or contact technical support—we’re here to help you find the right product for your application and can provide expert experimental support.

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Cas9 & gRNA Delivery Products

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CMV-hspCas9-T2A-Puro-H1-AAVS1_gRNA All-in-one Cas9 SmartNuclease™ & AAVS1 gRNA Lentivector

Streamline genome editing at the AAVS1 Safe Harbor Site in hard-to-transfect cells with a lentivector that expresses both Cas9 and an AAVS1-targeting gRNA
Sizes:
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All-in-one Cas9 SmartNuclease AAVS1 Targeting Lentivector (CMV-hspCas9-T2A-Puro-H1-AAVS1_gRNA)

" ["variation_id"]=> int(63436) ["variation_is_active"]=> bool(true) ["variation_is_visible"]=> bool(true) ["weight"]=> string(0) "" ["weight_html"]=> string(3) "N/A" } [1]=> array(24) { ["attributes"]=> array(1) { ["attribute_size"]=> string(10) "2 x 25 µL" } ["availability_html"]=> string(0) "" ["backorders_allowed"]=> bool(false) ["dimensions"]=> array(3) { ["length"]=> string(0) "" ["width"]=> string(0) "" ["height"]=> string(0) "" } ["dimensions_html"]=> string(3) "N/A" ["display_price"]=> float(595) ["display_regular_price"]=> float(595) ["image"]=> array(18) { ["title"]=> string(47) "all-in-one-lentivector-cas9-cmv-puro-aavs1-grna" ["caption"]=> string(0) "" ["url"]=> string(112) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-lentivector-cas9-cmv-puro-aavs1-grna.png" ["alt"]=> string(0) "" ["src"]=> string(112) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-lentivector-cas9-cmv-puro-aavs1-grna.png" ["srcset"]=> string(371) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-lentivector-cas9-cmv-puro-aavs1-grna.png 345w, https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-lentivector-cas9-cmv-puro-aavs1-grna-300x300.png 300w, https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-lentivector-cas9-cmv-puro-aavs1-grna-100x100.png 100w" ["sizes"]=> string(31) "(max-width: 345px) 100vw, 345px" ["full_src"]=> string(112) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-lentivector-cas9-cmv-puro-aavs1-grna.png" ["full_src_w"]=> int(345) ["full_src_h"]=> int(345) ["gallery_thumbnail_src"]=> string(120) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-lentivector-cas9-cmv-puro-aavs1-grna-100x100.png" ["gallery_thumbnail_src_w"]=> int(100) ["gallery_thumbnail_src_h"]=> int(100) ["thumb_src"]=> string(120) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-lentivector-cas9-cmv-puro-aavs1-grna-300x300.png" ["thumb_src_w"]=> int(300) ["thumb_src_h"]=> int(300) ["src_w"]=> int(345) ["src_h"]=> int(345) } ["image_id"]=> string(4) "7260" ["is_downloadable"]=> bool(false) ["is_in_stock"]=> bool(true) ["is_purchasable"]=> bool(true) ["is_sold_individually"]=> string(2) "no" ["is_virtual"]=> bool(false) ["max_qty"]=> string(0) "" ["min_qty"]=> int(1) ["price_html"]=> string(142) "$595" ["sku"]=> string(12) "CASLV601VA-1" ["variation_description"]=> string(152) "

All-in-one Cas9 SmartNuclease AAVS1 Targeting Lentivector (CMV-hspCas9-T2A-Puro-H1-AAVS1_gRNA) pre-packaged lentiviral particles (>10^6 IFUs)

" ["variation_id"]=> int(63437) ["variation_is_active"]=> bool(true) ["variation_is_visible"]=> bool(true) ["weight"]=> string(0) "" ["weight_html"]=> string(3) "N/A" } }
(Cat. # CASLV601PA-1), (Cat. # CASLV601VA-1)

All-in-one Cas9 SmartNuclease™ & AAVS1 gRNA Plasmid

Streamline genome editing at the AAVS1 Safe Harbor Site with a plasmid that expresses both Cas9 and a gRNA that targets the AAVS1 site
Size:
array(1) { [0]=> array(24) { ["attributes"]=> array(1) { ["attribute_size"]=> string(6) "10 µg" } ["availability_html"]=> string(0) "" ["backorders_allowed"]=> bool(false) ["dimensions"]=> array(3) { ["length"]=> string(0) "" ["width"]=> string(0) "" ["height"]=> string(0) "" } ["dimensions_html"]=> string(3) "N/A" ["display_price"]=> float(936) ["display_regular_price"]=> float(936) ["image"]=> array(18) { ["title"]=> string(34) "all-in-one-cas9-plasmid-aavs1-grna" ["caption"]=> string(0) "" ["url"]=> string(99) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-cas9-plasmid-aavs1-grna.png" ["alt"]=> string(0) "" ["src"]=> string(99) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-cas9-plasmid-aavs1-grna.png" ["srcset"]=> string(332) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-cas9-plasmid-aavs1-grna.png 345w, https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-cas9-plasmid-aavs1-grna-300x300.png 300w, https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-cas9-plasmid-aavs1-grna-100x100.png 100w" ["sizes"]=> string(31) "(max-width: 345px) 100vw, 345px" ["full_src"]=> string(99) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-cas9-plasmid-aavs1-grna.png" ["full_src_w"]=> int(345) ["full_src_h"]=> int(345) ["gallery_thumbnail_src"]=> string(107) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-cas9-plasmid-aavs1-grna-100x100.png" ["gallery_thumbnail_src_w"]=> int(100) ["gallery_thumbnail_src_h"]=> int(100) ["thumb_src"]=> string(107) "https://systembio.com/wp-content/uploads/crispr-cas9-systems/all-in-one-cas9-plasmid-aavs1-grna-300x300.png" ["thumb_src_w"]=> int(300) ["thumb_src_h"]=> int(300) ["src_w"]=> int(345) ["src_h"]=> int(345) } ["image_id"]=> string(4) "7259" ["is_downloadable"]=> bool(false) ["is_in_stock"]=> bool(true) ["is_purchasable"]=> bool(true) ["is_sold_individually"]=> string(2) "no" ["is_virtual"]=> bool(false) ["max_qty"]=> string(0) "" ["min_qty"]=> int(1) ["price_html"]=> string(142) "$936" ["sku"]=> string(9) "CAS601A-1" ["variation_description"]=> string(132) "

All-in-one plasmid to express Cas9 SmartNuclease and gRNA targeting the AAVS1 Safe Harbor Site (EF1α-hspCas9-H1-AAVS1_gRNA)

" ["variation_id"]=> int(63291) ["variation_is_active"]=> bool(true) ["variation_is_visible"]=> bool(true) ["weight"]=> string(0) "" ["weight_html"]=> string(3) "N/A" } }
(Cat. # CAS601A-1)

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