Mouse Complete SeraMir Exosome RNA Amplification & Profiling Kit for Media & Urine

Get a quick start on exoRNA profiling with everything you need to extract exoRNAs from most biofluids and test expression against 380 mouse miRs.

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Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800TC-1 with 50 mL ExoQuick-TC, RA805A-1, RA811A-1 components)

20 Profiles
$ 1442
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Get your exosomal RNA profiling studies off the ground fast

With everything you need for profiling exosomal RNAs from most biofluids, SBI’s Mouse Complete SeraMir Exosome RNA Amplification & Profiling Kit is a great way to get started with exoRNA profiling. The kit includes the fast and efficient ExoQuick-TC Exosome Isolation Reagent, phenol-free SeraMir exosome RNA purification reagents and columns, reagents for cDNA synthesis and amplification, and one 384-well plate with mouse miRNAs and control wells for quantitation of isolated exoRNAs. (NOTE: for exoRNA isolation from serum, plasma, or ascites fluid, try the Mouse Complete SeraMir Kit).

  • Reliable, reproducible exoRNA isolation from most biofluids
  • Sensitive detection via exoRNA amplification
  • Everything you need including 384-well plate of mouse miRNAs for qPCR profiling

To find out which miRNAs are included, click here.

Find exosomal RNA biomarkers using the SeraMir Exosome RNA Amplification KitChoose the SeraMir Kit that’s right for you

Cat. # Name Kit includes
ExoQuick or ExoQuick-TC SeraMir RNA columns and reagents SeraMir cDNA synthesis and amplification reagents 384-well plate miRNAs for human, mouse, or rat
RA800A-1 Complete SeraMir Exosome RNA Amplification Kit  
RA800TC-1 Complete SeraMir Exosome RNA Amplification Kit for Media and Urine  
RA806A-1 SeraMir Exosome RNA Purification Kit    
RA806TC-1 SeraMir Exosome RNA Purification Kit for Media and Urine    
RA808A-1 SeraMir Exosome RNA Purification Column Kit      
RA820A-1 Human Complete SeraMir Exosome RNA Amplification and Profiling Kit
RA820TC-1 Human Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine
RA821A-1 Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit
RA821TC-1 Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine
RA822A-1 Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit
RA822TC-1 Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine

How It Works

Quickly and easily profile exoRNAs

  • Isolate exosomes from patient biofluids with the included ExoQuick-TC reagent
  • Purify exoRNAs with SeraMir columns
  • Measure expression levels of 380 mouse miRNAs in a 384-well qPCR assay

Isolate serum exosomes and purify exoRNAs

Streamline biomarker discovery with seramir – the workflow, steps 1 and 2

Tail exoRNAs and synthesize double-tagged cDNAStreamline biomarker discovery with seramir – the workflow, steps 3 and 4

Three validated reference controls included on the SeraMir Profiling qPCR plateMouse miRNA profiling qPCR plate includes three validated reference controls

Excellent technical replicates across an 8-log rangeExcellent technical replicates across 8 logs

Supporting Data

Better qPCR profiling with SeraMir

SeraMir provides reliably better qPCR profiling than exosmal RNAs isolated using phenol/trizol

Figure 1. Serum RNA prepared by the SeraMir Kit delivers more reliable, reproducible qPCR profiles than when the RNA is isolated using conventional Trizol methods. Profiling of 380 human microRNAs across the SeraMir 384 Profiler. The phenol-free exosome lysis step coupled to the small RNA binding columns isolates exoRNAs with much higher purity than Trizol/Phenol based methods. The SeraMir exoRNAs are compatible with downstream polyadenylation and reverse trancription reactions for amplification and accurate qPCR profiling.

 SeraMir provides reliably better qPCR profiling than exosomal RNAs isolated using phenol/trizol

Figure 2. Serum exoRNAs prepared using SeraMir deliver excellent performance in microarray studies. Samples from a pooled normal serum preparation and from a male caucasian (age 73) with adenocarcinoma of the colon were used in this study. Exosomes were precipitated from 250 µL of serum using the SeraMir Exosome RNA Amplification Kit. The T7-amplified “sense” exoRNAs were then used for direct labeling analyses on LC Sciences miRBase ver.16 array chips (performed in triplicate). The exoRNAs were hybridized across 1,214 different microRNAs on the probe set.
Of the 1,214 microRNAs analyzed, 79 microRNAs showed a signal intensity >32. Within this set of 79, there was a clear colon versus normal “signature set” of 40 microRNAs that could discriminate normal from colon cancer serum samples with a p-value < 0.01. The identities of the microRNAs found in this study have been masked while further investigation continues.


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