Exosome Size and Features

As mentioned before, an exosome’s size ranges from 30-100 nanometers and these vesicles can be secreted by a wide range of cells; where their composition will depend strongly on their cell of origin.

Of note, virtually all mammalian cells that have been studied exhibit exosome-based communication.

And as with these cells, an exosome’s contents are likewise going to be quite varied. This is because exosomal contents can include proteins such as enzymes, as well as mRNAs and ncRNAs, lipids, and much more (Diagram 1.3)

Diagram 1.3: Exosome Features.