miRZip Knockdown Vectors

Permanently knockdown miRs with SBI’s miRZip anti-miRNA Expression Lentivectors

Leveraging SBI’s powerful and well-regarded third-generation lentivector technology, each of our miRZip lentivectors expresses a short hairpin RNA (shRNA) that, after processing, preferentially produces an anti-sense miRNA. The hairpin is rationally designed to be asymmetric, ensuring that the sense strand does not contain the endogenous miRNA sequence and enabling accumulation of the anti-miRNA. The result is robust derepression of the transcripts targeted by the microRNA being “zipped,” and elevation of the corresponding protein levels.

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miRZip Knockdown Vectors

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miRZip™ & pGreenPuro™ shRNA Scramble Hairpin Negative Control

Easily get the confidence of a good negative control for your miRZip and pGreenPuro shRNA studies with this scrambled, non-targeting pre-miRNA Lentivector
Sizes:
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"https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-600x600.png 600w, https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-300x300.png 300w, https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-100x100.png 100w" ["sizes"]=> string(31) "(max-width: 600px) 100vw, 600px" ["full_src"]=> string(118) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01.png" ["full_src_w"]=> int(2500) ["full_src_h"]=> int(2500) ["gallery_thumbnail_src"]=> string(126) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-100x100.png" ["gallery_thumbnail_src_w"]=> int(100) ["gallery_thumbnail_src_h"]=> int(100) ["thumb_src"]=> string(126) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-300x300.png" ["thumb_src_w"]=> int(300) ["thumb_src_h"]=> int(300) ["src_w"]=> int(600) ["src_h"]=> int(600) } ["image_id"]=> string(5) "20984" ["is_downloadable"]=> bool(false) ["is_in_stock"]=> bool(true) ["is_purchasable"]=> bool(true) ["is_sold_individually"]=> string(2) "no" ["is_virtual"]=> bool(false) ["max_qty"]=> string(0) "" ["min_qty"]=> int(1) ["price_html"]=> string(142) "$544" ["sku"]=> string(12) "MZIP000-PA-1" ["variation_description"]=> string(0) "" ["variation_id"]=> int(93853) ["variation_is_active"]=> bool(true) ["variation_is_visible"]=> bool(true) ["weight"]=> string(0) "" ["weight_html"]=> string(3) "N/A" } [1]=> array(24) { ["attributes"]=> array(2) { ["attribute_pa_choose-product"]=> string(64) "pgreenpuro-scramble-hairpin-control-virus-for-shrnas-and-mirzips" ["attribute_pa_size"]=> string(12) "1-x-106-ifus" } ["availability_html"]=> string(0) "" ["backorders_allowed"]=> bool(false) ["dimensions"]=> array(3) { ["length"]=> string(0) "" ["width"]=> string(0) "" ["height"]=> string(0) "" } ["dimensions_html"]=> string(3) "N/A" ["display_price"]=> float(598) ["display_regular_price"]=> float(598) ["image"]=> array(18) { ["title"]=> string(73) "miRZip™ & pGreenPuro™ shRNA Scramble Hairpin Negative Control" ["caption"]=> string(0) "" ["url"]=> string(118) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01.png" ["alt"]=> string(0) "" ["src"]=> string(126) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-600x600.png" ["srcset"]=> string(397) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-600x600.png 600w, https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-300x300.png 300w, https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-100x100.png 100w" ["sizes"]=> string(31) "(max-width: 600px) 100vw, 600px" ["full_src"]=> string(118) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01.png" ["full_src_w"]=> int(2500) ["full_src_h"]=> int(2500) ["gallery_thumbnail_src"]=> string(126) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-100x100.png" ["gallery_thumbnail_src_w"]=> int(100) ["gallery_thumbnail_src_h"]=> int(100) ["thumb_src"]=> string(126) "https://systembio.com/wp-content/uploads/mirna-lncrna-research/mirzip-pgreenpuro-shrna-scramble-hairpin-control-01-300x300.png" ["thumb_src_w"]=> int(300) ["thumb_src_h"]=> int(300) ["src_w"]=> int(600) ["src_h"]=> int(600) } ["image_id"]=> string(5) "20984" ["is_downloadable"]=> bool(false) ["is_in_stock"]=> bool(true) ["is_purchasable"]=> bool(true) ["is_sold_individually"]=> string(2) "no" ["is_virtual"]=> bool(false) ["max_qty"]=> string(0) "" ["min_qty"]=> int(1) ["price_html"]=> string(142) "$598" ["sku"]=> string(12) "MZIP000-VA-1" ["variation_description"]=> string(0) "" ["variation_id"]=> int(93854) ["variation_is_active"]=> bool(true) ["variation_is_visible"]=> bool(true) ["weight"]=> string(0) "" ["weight_html"]=> string(3) "N/A" } }
Bacterial Streak (Cat. # MZIP000-PA-1), >1 x 10^6 IFUs (Cat. # MZIP000-VA-1)

miRZip™ Pooled Anti-miRNA Virus Library

Efficiently conduct high-throughput phenotypic screens by quickly building stable cell lines where a specific miR is knocked down.
Size:
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1 Virus Aliquot (Cat. # MZIPPLVA-1)

miRZip™ anti-miRNA Expression Lentivectors

Study miRNA function by permanently knocking-down activity of a specific miRNA
Available product versions (242)

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