Overview
Get greater insights from in vivo studies with luciferase-labeled cell lines
While SBI already offers a number of ready-to-go reporter cell lines, everyone’s studies are different. Which is why SBI also offers Custom Stable Reporter Cell Line Services that can generate promoter- and/or enhancer-reporter fusions. Save time and effort while leveraging our comprehensive range of technologies and our expert team which has years of experience working with a variety of cell lines, including adherent and suspension cells.
Why choose SBI’s Stable Cell Line Services?
- Save time by having SBI build your custom cell lines
- Leverage our highly-regarded gene expression and delivery technologies
- Accomplish more with our fast turnaround times and end-to-end services
- Turn to the company that other companies turn to—we are a trusted stable cell line manufacturer for many large pharma/biotech companies
- Enjoy consistent quality, confidentiality, and on-time delivery with all projects completed on-site in our Palo Alto, CA, facility
Available gene expression and delivery technologies
Viral Systems
- Lentivectors—high titer and reliable
- Random integration
- Limited insert size
- High copy number
- Lentivirus Packaging—reliable gene delivery
- High and ultra-high titers
- Efficient transduction
- Optimized reagents
Non-viral Systems
- PhiC31 Integrase System—one-step single-copy integration
- Site-specific integration
- Unlimited insert size
- Single copy number
- PinPoint Targeted Integration System—excellent for creating isogenic cell lines
- Site-specific integration
- Unlimited insert size
- Single copy number
Not sure what you need or where to begin? Contact the services team to set up a complimentary phone consultation—email services@systembio.com.
Supporting Data
Successful generation of dual luciferase and GFP-labeled NF-κB cell line
SBI Website Content/04_Services Pages/Z_Services Image Files/GFP_induce.jpg, Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI Monitor and quantitatively measure NF-κB transactivation in live cells]
, Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI Monitor and quantitatively measure NF-κB transactivation in live cells" />
Figure 1. Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI—monitor and quantitatively measure NFκB transactivation in live cells. Monitor NF-κB activation in real time with GFP using SBI’s NF-κB/293/GFP-Luc™ Transcriptional Reporter Cell Line (Cat.# TR860A-1).
Figure 2. Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI—monitor and quantitatively measure NFκB transactivation in live cells. Quantitatively measure NF-κB activation in real time with luciferase using SBI’s NF-κB/293/GFP-Luc Transcriptional Reporter Cell Line (Cat.# TR860A-1).
