Integrase-based Systems
When you want non-viral expression from low or single-copy integration events, and/or have a large insert size, choose one of SBI’s integrase-based systems
Choose one of SBI’s integrase-based gene expression systems when you want a non-viral system that integrates at low- or single-copy. Both our PhiC31 and PinPoint Systems support unlimited insert sizes, and come in a variety of promoter and reporter combinations.
The PhiC31 Integrase System
- Frequently used for gene therapy development and related applications
- Non-viral transgene delivery
- Single-step process
- Single-copy integration
- Preferential integration at active sites
- Delivery of inserts with no size constraints
- Easy generation of cell lines
The PinPoint Targeted Integration System
- Isogenic cell line creation
- Reliable and efficient cell line generation and retargeting
- Non-viral transgene delivery
- Two-step process
- High-efficiency, site-specific, single-copy integration
- Delivery of inserts with no size constraints
- Compatible with high-throughput workflows