Exosome Engineering

When you’re ready to move from simply studying exosomes to using them as research tools, SBI offers a complete set of products for exosome engineering

Used by cells to transport cargoes of active biomolecules, exosomes are emerging as a powerful way for scientists to deliver specific proteins and miRNAs to target cells. As the field transitions from observation and analysis of exosomes to custom exosome design for therapeutics and other uses, SBI is already offering the necessary tools to push exosome engineering to the next level. With today’s family of products, you can:

  • Deliver miRNA for knockdown studies with XMIRs and AXMIRs
  • Transfect nucleic acids, proteins, and even small molecules into exosomes using Exo-Fect
  • Tag proteins for loading into exosomes using XPack
  • Facilitate uptake of exosomes by cells using EV Shuttle and EV Entry Kits
  • Target exosomes to specific tissues with XSTAMP

With SBI’s Exosome Engineering products, the possible uses for exosomes are limited only by your imagination.

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Exosome Engineering Products

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Exo-Fect™ siRNA/miRNA Transfection Kit

Achieve reliable & reproducible loading of siRNAs and miRNAs into extracellular vesicles with SBI’s high-efficiency Exo-Fect™ siRNA/miRNA Transfection Kit.
Size:20 Reactions (Cat. # EXFT200A-1)

XStamp™ Pro Streptavidin Customizable EV Targeting Kit

Quickly and easily create custom targeted EVs with XStamp Pro Streptavidin — no cloning necessary!
Size:10 Reactions (Cat. # XSTP900A-1)

XStamp™ Pro anti-HIV EV Targeting Kit

Engineer EVs to deliver cargo to HIV-infected cells with XStamp Pro anti-HIV, a streamlined method for adding target cell specificity to already-purified EVs
Size:10 Reactions (Cat. # XSTP905A-1)

XStamp™ Pro anti-CD16 EV Targeting Kit

Engineer EVs to deliver cargo to cells expressing CD16 on their surface using the streamlined XStamp Pro anti-CD16 workflow—works with already-purified EVs
Size:10 Reactions (Cat. # XSTP910A-1)

XStamp™ Pro anti-PD-1 EV Targeting Kit

Engineer EVs to deliver cargo to cells expressing PD-1 on their surface using the streamlined XStamp Pro PD-1 workflow—works with already-purified EVs
Size:10 Reactions (Cat. # XSTP915A-1)

XPack-GFP-loaded HEK293 Exosomes

Deliver GFP to cells or simply track GFP-labeled exosomes with our ready-to-use XPack-GFP-loaded HEK293 Exosomes.
Size:50 µg Exosomes (Cat. # XPAK100EX-G)

XPack CMV-XP-MCS-EF1α-Puro Cloning Lentivector

Package your protein-of-interest into exosomes with the XPack CMV-XP-MCS-EF1α-Puro Cloning Lentivector—great for delivering protein to target cells and more.
Size:10 µg (Cat. # XPAK510PA-1)

XPack CMV-XP-GFP-EF1α-Puro Expression Lentivector

Label exosomes with GFP and track uptake into target cells with XPack CMV-XP-GFP-EF1α-Puro Expression Lentivector.
Sizes:2 x 10^6 Cells (Cat. # XPAK530CL-1), 10 µg (Cat. # XPAK530PA-1), >1 x 10^6 IFUs (Cat. # XPAK530VA-1)

XPack CMV-XP-RFP-EF1α-Puro Expression Lentivector

Label exosomes with RFP and track uptake into target cells with XPack CMV-XP-RFP-EF1α-Puro Expression Lentivector.
Size:10 µg (Cat. # XPAK531PA-1)

XPack CMV-XP-Luciferase-EF1α-Puro Expression Lentivector

Label exosomes with luciferase and track uptake into target cells with XPack CMV-XP-Luciferase-EF1α-Puro Expression Lentivector.
Sizes:2 x 10^6 Cells (Cat. # XPAK532CL-1), 10 µg (Cat. # XPAK532PA-1), >1 x 10^6 IFUs (Cat. # XPAK532VA-1)

XPack MSCV-XP-MCS-EF1α-Puro Cloning Lentivector

Package your protein-of-interest into exosomes with the XPack MSCV-XP-MCS-EF1α-Puro Cloning Lentivector—great for delivering protein to target cells and more.
Size:10 µg (Cat. # XPAK710PA-1)

XPack MSCV-XP-GFP-EF1α-Puro Expression Lentivector

Label exosomes with GFP and track uptake into target cells with XPack MSCV-XP-GFP-EF1α-Puro Expression Lentivector.
Sizes:10 µg (Cat. # XPAK730PA-1), >1 x 10^6 IFUs (Cat. # XPAK730VA-1)

XPack MSCV-XP-RFP-EF1α-Puro Expression Lentivector

Label exosomes with RFP and track uptake into target cells with XPack MSCV-XP-RFP-EF1α-Puro Expression Lentivector.
Size:10 µg (Cat. # XPAK731PA-1)

XPack MSCV-XP-Luciferase-EF1α-Puro Expression Lentivector

Label exosomes with luciferase and track uptake into target cells with XPack MSCV-XP-Luciferase-EF1α-Puro Expression Lentivector.
Sizes:10 µg (Cat. # XPAK732PA-1), >1 x 10^6 IFUs (Cat. # XPAK732VA-1)

Exo-Fect™ Exosome Transfection Kit

Turn your exosomes into delivery vehicles with Exo-Fect—enables insertion of RNAs, DNAs (including plasmids), and small molecules into isolated exosomes.
Sizes:10 Reactions (Cat. # EXFT10A-1), 20 Reactions (Cat. # EXFT20A-1)

EV-Entry System

Increase the efficiency of cellular uptake and cargo unloading of extracellular vesicles with the EV-Entry System
Sizes:5 Reactions (Cat. # EVEN105A-1), 10 Reactions (Cat. # EVEN110A-1)

EV Shuttle Kit with HEK293 Exosomes

Put exosomes to work—directly transfect HEK293 exosomes with RNA, plasmids, metabolites, or other small molecules for delivery to recipient cells.
Sizes:5 Reactions (Cat. # EVS105A-1), 10 Reactions (Cat. # EVS110A-1)

EV Shuttle Kit with JAWS II Mouse Bone Marrow Dendritic Cell Exosomes

Put exosomes to work—directly transfect JAWS II exosomes with RNA, plasmids, metabolites, or other small molecules for delivery to recipient cells.
Sizes:5 Reactions (Cat. # EVS205A-1), 10 Reactions (Cat. # EVS210A-1)

XStamp™-GE11 Lentivector for Targeting Exosomes to Cancer Cells

Target exosomes to cancer cells with the pre-built XStamp-GE11 Lentivector Construct (binds to cells expressing EGFR).
Size:10 µg (Cat. # XSTP723PA-1)

XStamp™-HER2 Lentivector for Targeting Exosomes to Breast Cancer Cells

Target exosomes to breast cancer cells with the pre-built XStamp-HER2 Lentivector Construct.
Size:10 µg (Cat. # XSTP724PA-1)

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