PEG-it Virus Precipitation Solution
Products
Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
---|---|---|---|---|---|---|---|---|
LV810A-1 | PEG-it Virus Precipitation Solution | 100 mL | $337 |
|
||||
LV825A-1 | PEG-it Virus Precipitation Solution | 250 mL | $737 |
|
Overview
Overview
Easily concentrate lentivirus particles for ultra-high titers
Used in over three-hundred citations, PEG-it™ Virus Concentration Reagent enables easy concentration of pseudoviral particles for achieving ultra-high titers. It’s great for concentrating pseudoviral particles even from large volumes of medium by removing the need for ultracentrifugation. Simply add PEG-it to the collected medium, incubate overnight at 4°C, and spin at 1500g for 30 minutes.
In addition, PEG-it acts as a cryopreservative for concentrated virus. Lentivirus concentrated with PEG-it lasts longer in the freezer and survives multiple freeze-thaw cycles with minimal loss of titer.
References
How It Works
Supporting Data
FAQs
- Concentrates virus particles 10- to 100-fold, leading to higher infectious units per mL
- Eliminates the need for ultracentrifugation
- Non-toxic and effective with stem cells
- Acts as a cryopreservative, protecting the virus from multiple freeze-thaw cycles with minimal loss of titer
100 mL (Catalog Number: LV810A-1)
250 mL (Catalog Number: LV825A-1)
Related Products
Resources
Citations
-
An, M, et al. (2024) Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo. Nature biotechnology. 2024;. PM ID: 38191664
-
Ullah, I, et al. (2024) Bioluminescence Imaging Reveals Enhanced SARS-CoV-2 Clearance in Mice with Combinatorial Regimens. iScience. 2024;:109049. Link: iScience
-
Baudrier, L, et al. (2024) One-pot DTECT enables rapid and efficient capture of genetic signatures for precision genome editing and clinical diagnostics. Cell reports methods. 2024;:100698. PM ID: 38301655
-
Konishi, CT, et al. (2024) Modeling and Correction of Protein Conformational Disease in iPSC-derived Neurons through Personalized Base Editing. bioRxiv : the preprint server for biology. 2024;. PM ID: 38293034
-
Yang, L, et al. (2024) Tissue-location-specific transcription programs drive tumor dependencies in colon cancer. Nature communications. 2024; 15(1):1384. PM ID: 38360902
-
Vella, V, et al. (2024) Kinome-Wide Synthetic Lethal Screen Identifies PANK4 as a Modulator of Temozolomide Resistance in Glioblastoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024;:e2306027. PM ID: 38353396
-
Lau, C, et al. (2024) Lentiviral expression of wildtype LAMA3A restores cell adhesion in airway basal cells from children with epidermolysis bullosa. Molecular Therapy. 2024;. Link: Molecular Therapy
-
Pahl, MC, et al. (2024) Variant to gene mapping for carpal tunnel syndrome risk loci implicates skeletal muscle regulatory elements. EBioMedicine. 2024; 101:105038. PM ID: 38417377
-
Mueller, J, et al. (2024) Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells. EMBO molecular medicine. 2024;. PM ID: 38355749
-
Jin, Y, et al. (2024) Tsyn-seq: a T cell synapse-based antigen identification platform. Cancer immunology research. 2024;. PM ID: 38363296
-
Tian, Y, et al. (2024) mRNA nuclear retention reduces AMPAR expression and promotes autistic behavior in UBE3A-overexpressing mice. EMBO reports. 2024;. PM ID: 38316900
-
Joshi, VR, et al. (2024) A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope. Journal of virology. 2024;:e0172023. PM ID: 38412036
-
Yoshida, T, et al. (2024) HIV-1 RNAs whose transcription initiates from the third deoxyguanosine of GGG tract in the 5′ long terminal repeat serve as a dominant genome for efficient provirus DNA formation. Journal of virology. 2024; 98(2):e0182523. PM ID: 38289105
-
Hillenbrand, M, et al. (2024) Fast-Track Discovery of SARS-CoV-2-Neutralizing Antibodies from Human B Cells by Direct Functional Screening. Viruses. 2024; 16(3):339. Link: Viruses
-
Kawamura, T, et al. (2024) BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells. Reproduction (Cambridge, England). 2024; 167(2). PM ID: 38271820
-
Kent, M, Jay, A & Kendall, G. (2024) New Dual Inducible Cellular Model to Investigate Temporal Control of Oncogenic Cooperating Genes. bioRxiv. 2024;. Link: bioRxiv
-
Barisic, D, et al. (2024) ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis. Cancer cell. 2024;. PM ID: 38458187
-
Yang, Y, et al. (2024) Low-dose targeted radionuclide therapy synergizes with CAR T cells and enhances tumor response. Frontiers in immunology. 2024; 15:1355388. PM ID: 38550578
-
Li, Y, et al. (2024) Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages. PLoS pathogens. 2024; 20(3):e1012079. PM ID: 38466743
-
Gardner, Z, et al. (2024) The role of glia in the dysregulation of neuronal spinogenesis in Ube3a-dependent ASD. Experimental neurology. 2024; 376:114756. PM ID: 38508482
- See More
Products
Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
---|---|---|---|---|---|---|---|---|
LV810A-1 | PEG-it Virus Precipitation Solution | 100 mL | $337 |
|
||||
LV825A-1 | PEG-it Virus Precipitation Solution | 250 mL | $737 |
|
Overview
Overview
Easily concentrate lentivirus particles for ultra-high titers
Used in over three-hundred citations, PEG-it™ Virus Concentration Reagent enables easy concentration of pseudoviral particles for achieving ultra-high titers. It’s great for concentrating pseudoviral particles even from large volumes of medium by removing the need for ultracentrifugation. Simply add PEG-it to the collected medium, incubate overnight at 4°C, and spin at 1500g for 30 minutes.
In addition, PEG-it acts as a cryopreservative for concentrated virus. Lentivirus concentrated with PEG-it lasts longer in the freezer and survives multiple freeze-thaw cycles with minimal loss of titer.
References
FAQs
- Concentrates virus particles 10- to 100-fold, leading to higher infectious units per mL
- Eliminates the need for ultracentrifugation
- Non-toxic and effective with stem cells
- Acts as a cryopreservative, protecting the virus from multiple freeze-thaw cycles with minimal loss of titer
100 mL (Catalog Number: LV810A-1)
250 mL (Catalog Number: LV825A-1)
Citations
-
An, M, et al. (2024) Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo. Nature biotechnology. 2024;. PM ID: 38191664
-
Ullah, I, et al. (2024) Bioluminescence Imaging Reveals Enhanced SARS-CoV-2 Clearance in Mice with Combinatorial Regimens. iScience. 2024;:109049. Link: iScience
-
Baudrier, L, et al. (2024) One-pot DTECT enables rapid and efficient capture of genetic signatures for precision genome editing and clinical diagnostics. Cell reports methods. 2024;:100698. PM ID: 38301655
-
Konishi, CT, et al. (2024) Modeling and Correction of Protein Conformational Disease in iPSC-derived Neurons through Personalized Base Editing. bioRxiv : the preprint server for biology. 2024;. PM ID: 38293034
-
Yang, L, et al. (2024) Tissue-location-specific transcription programs drive tumor dependencies in colon cancer. Nature communications. 2024; 15(1):1384. PM ID: 38360902
-
Vella, V, et al. (2024) Kinome-Wide Synthetic Lethal Screen Identifies PANK4 as a Modulator of Temozolomide Resistance in Glioblastoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024;:e2306027. PM ID: 38353396
-
Lau, C, et al. (2024) Lentiviral expression of wildtype LAMA3A restores cell adhesion in airway basal cells from children with epidermolysis bullosa. Molecular Therapy. 2024;. Link: Molecular Therapy
-
Pahl, MC, et al. (2024) Variant to gene mapping for carpal tunnel syndrome risk loci implicates skeletal muscle regulatory elements. EBioMedicine. 2024; 101:105038. PM ID: 38417377
-
Mueller, J, et al. (2024) Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells. EMBO molecular medicine. 2024;. PM ID: 38355749
-
Jin, Y, et al. (2024) Tsyn-seq: a T cell synapse-based antigen identification platform. Cancer immunology research. 2024;. PM ID: 38363296
-
Tian, Y, et al. (2024) mRNA nuclear retention reduces AMPAR expression and promotes autistic behavior in UBE3A-overexpressing mice. EMBO reports. 2024;. PM ID: 38316900
-
Joshi, VR, et al. (2024) A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope. Journal of virology. 2024;:e0172023. PM ID: 38412036
-
Yoshida, T, et al. (2024) HIV-1 RNAs whose transcription initiates from the third deoxyguanosine of GGG tract in the 5′ long terminal repeat serve as a dominant genome for efficient provirus DNA formation. Journal of virology. 2024; 98(2):e0182523. PM ID: 38289105
-
Hillenbrand, M, et al. (2024) Fast-Track Discovery of SARS-CoV-2-Neutralizing Antibodies from Human B Cells by Direct Functional Screening. Viruses. 2024; 16(3):339. Link: Viruses
-
Kawamura, T, et al. (2024) BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells. Reproduction (Cambridge, England). 2024; 167(2). PM ID: 38271820
-
Kent, M, Jay, A & Kendall, G. (2024) New Dual Inducible Cellular Model to Investigate Temporal Control of Oncogenic Cooperating Genes. bioRxiv. 2024;. Link: bioRxiv
-
Barisic, D, et al. (2024) ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis. Cancer cell. 2024;. PM ID: 38458187
-
Yang, Y, et al. (2024) Low-dose targeted radionuclide therapy synergizes with CAR T cells and enhances tumor response. Frontiers in immunology. 2024; 15:1355388. PM ID: 38550578
-
Li, Y, et al. (2024) Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages. PLoS pathogens. 2024; 20(3):e1012079. PM ID: 38466743
-
Gardner, Z, et al. (2024) The role of glia in the dysregulation of neuronal spinogenesis in Ube3a-dependent ASD. Experimental neurology. 2024; 376:114756. PM ID: 38508482
- See More