TransDux™ (Original) Virus Transduction Reagent
- High transduction efficiency
- Broad cell type compatibility
- Minimal hands-on time
Products
| Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
|---|---|---|---|---|---|---|---|---|
| LV850A-1 | TransDux virus transduction reagent (200x) | 100 Transductions | $267 |
|
||||
Overview
Overview
Infect more cells with TransDux™
Increase your transduction efficiencies with TransDux (Original) Virus Transduction Reagent. Simply mix with virus to see 2-fold or greater (depending on cell type) transduction efficiencies over polybrene addition.
Or try our newer TransDux MAX™ Virus Transduction Reagent for an even greater increase in infectivity.
- High transduction efficiency
- Broad cell type compatibility
- Minimal hands-on time
How It Works
How It Works
Get higher transduction efficiencies with minimal hands-on time
Simply combine culture medium with TransDux to a final concentration of 1x, add to cells, and then add virus. Swirl to mix, and proceed with the transduction as usual—72-hours post transduction, the viral genome will be integrated into the host cell genome.
Supporting Data
Supporting Data
Increase transduction efficiencies with TransDux
Figure 1. Our original TransDux Reagent increases transduction efficiencies at least 2-fold compared to polybrene. Transduction of either HepG2 cells (top panels) or HT1080 cells (bottom panels) with the addition of polybrene (left two panels) or TransDux (middle two panels). The right two panels show quantitative measures of infectivity using the Global UltraRapid Titer Kit. Both imaging and infectivity data show that TransDux increased the infectivity of lentivirus in both cell types as compared to polybrene.
FAQs
Resources
Related Products
Citations
-
Eisfeld, AK, et al. (2017) Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemia.. Leukemia. 2017; 31(6):1278-1285. PM ID: 27843138
-
Swiercz, R, et al. (2017) Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption. Oncotarget. 2017; 8(2):3528-3541. PM ID: 27974681
-
Lin, ZY, et al. (2017) MicroRNA-30d promotes angiogenesis and tumor growth via MYPT1/c-JUN/VEGFA pathway and predicts aggressive outcome in prostate cancer. Mol. Cancer. 2017; 16(1):48. PM ID: 28241827
-
Zeng, Q, et al. (2017) Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. Proc. Natl. Acad. Sci. U.S.A.. 2017; 114(7):1631-1636. PM ID: 28137840
-
Takahashi, H, et al. (2017) Autophagy is required for cell survival under L-asparaginase-induced metabolic stress in acute lymphoblastic leukemia cells. Oncogene. 2017;. PM ID: 28346428
-
Song, R, et al. (2017) An epigenetic regulatory loop controls pro-osteogenic activation by TGF-β1 or bone morphogenetic protein 2 in human aortic valve interstitial cells. J. Biol. Chem.. 2017; 292(21):8657-8666. PM ID: 28377507
-
Mo, RJ, et al. (2017) Decreased HoxD10 expression promotes a proliferative and aggressive phenotype in prostate cancer. Curr. Mol. Med.. 2017;. PM ID: 28231752
-
Song, R, et al. (2017) Altered MicroRNA Expression Is Responsible for the Pro-Osteogenic Phenotype of Interstitial Cells in Calcified Human Aortic Valves. J Am Heart Assoc. 2017; 6(4). PM ID: 28438736
-
Li, P, et al. (2017) SIRT1 is required for mitochondrial biogenesis reprogramming in hypoxic human pulmonary arteriolar smooth muscle cells. Int. J. Mol. Med.. 2017; 39(5):1127-1136. PM ID: 28339017
-
Lopez, CM. (2017) MiR-34a Regulates the Invasive Capacity of Canine Osteosarcoma Cell Lines. Thesis. 2017;. Link: Thesis
-
Liang, YX, et al. (2016) E2F1 promotes tumor cell invasion and migration through regulating CD147 in prostate cancer. Int. J. Oncol.. 2016; 48(4):1650-8. PM ID: 26891801
-
Li, Q, et al. (2016) Development and Validation of a Rex1-RFP Potency Activity Reporter Assay That Quantifies Stress-Forced Potency Loss in Mouse Embryonic Stem Cells.. Stem Cells Dev.. 2016; 25(4):320-8. PM ID: 26651054
-
Li, Q, et al. (2016) High-Throughput Screens for Embryonic Stem Cells: Stress-Forced Potency-Stemness Loss Enables Toxicological Assays. Protocol. 2016;:1-34. Link: Protocol
-
Lesnik, J, et al. (2016) Registered report: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Elife. 2016; 5:e07383. PM ID: 26826285
-
Irvine, DA, et al. (2016) Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia. Sci Rep. 2016; 6:25476. PM ID: 27157927
-
Chen, Y, et al. (2016) Calcineurin β protects brain after injury by activating the unfolded protein response. Neurobiol. Dis.. 2016; 94:139-56. PM ID: 27334877
-
Tilghman, J, et al. (2016) Regulation of Glioblastoma Tumor-Propagating Cells by the Integrin Partner Tetraspanin CD151. Neoplasia. 2016; 18(3):185-98. PM ID: 26992919
-
Westbroek, W, et al. (2016) A new glucocerebrosidase-deficient neuronal cell model provides a tool to probe pathophysiology and therapeutics for Gaucher disease. Dis Model Mech. 2016; 9(7):769-78. PM ID: 27482815
-
Shrivastava, S, et al. (2016) The Role of HMGB1 in Radioresistance of Bladder Cancer. Mol. Cancer Ther.. 2016; 15(3):471-9. PM ID: 26719575
-
Zhou, A, et al. (2016) RNA Binding Protein HuR Regulates Cardiac Sodium Channel Gene (SCN5A) Expression Through Transcriptional and Post-Transcriptional Pathways. Circulation. 2016; 134(1):A14386. Link: Circulation
- See More
Products
| Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
|---|---|---|---|---|---|---|---|---|
| LV850A-1 | TransDux virus transduction reagent (200x) | 100 Transductions | $267 |
|
||||
Overview
Overview
Infect more cells with TransDux™
Increase your transduction efficiencies with TransDux (Original) Virus Transduction Reagent. Simply mix with virus to see 2-fold or greater (depending on cell type) transduction efficiencies over polybrene addition.
Or try our newer TransDux MAX™ Virus Transduction Reagent for an even greater increase in infectivity.
- High transduction efficiency
- Broad cell type compatibility
- Minimal hands-on time
How It Works
How It Works
Get higher transduction efficiencies with minimal hands-on time
Simply combine culture medium with TransDux to a final concentration of 1x, add to cells, and then add virus. Swirl to mix, and proceed with the transduction as usual—72-hours post transduction, the viral genome will be integrated into the host cell genome.
Supporting Data
Supporting Data
Increase transduction efficiencies with TransDux
Figure 1. Our original TransDux Reagent increases transduction efficiencies at least 2-fold compared to polybrene. Transduction of either HepG2 cells (top panels) or HT1080 cells (bottom panels) with the addition of polybrene (left two panels) or TransDux (middle two panels). The right two panels show quantitative measures of infectivity using the Global UltraRapid Titer Kit. Both imaging and infectivity data show that TransDux increased the infectivity of lentivirus in both cell types as compared to polybrene.
FAQs
Citations
-
Eisfeld, AK, et al. (2017) Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemia.. Leukemia. 2017; 31(6):1278-1285. PM ID: 27843138
-
Swiercz, R, et al. (2017) Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption. Oncotarget. 2017; 8(2):3528-3541. PM ID: 27974681
-
Lin, ZY, et al. (2017) MicroRNA-30d promotes angiogenesis and tumor growth via MYPT1/c-JUN/VEGFA pathway and predicts aggressive outcome in prostate cancer. Mol. Cancer. 2017; 16(1):48. PM ID: 28241827
-
Zeng, Q, et al. (2017) Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. Proc. Natl. Acad. Sci. U.S.A.. 2017; 114(7):1631-1636. PM ID: 28137840
-
Takahashi, H, et al. (2017) Autophagy is required for cell survival under L-asparaginase-induced metabolic stress in acute lymphoblastic leukemia cells. Oncogene. 2017;. PM ID: 28346428
-
Song, R, et al. (2017) An epigenetic regulatory loop controls pro-osteogenic activation by TGF-β1 or bone morphogenetic protein 2 in human aortic valve interstitial cells. J. Biol. Chem.. 2017; 292(21):8657-8666. PM ID: 28377507
-
Mo, RJ, et al. (2017) Decreased HoxD10 expression promotes a proliferative and aggressive phenotype in prostate cancer. Curr. Mol. Med.. 2017;. PM ID: 28231752
-
Song, R, et al. (2017) Altered MicroRNA Expression Is Responsible for the Pro-Osteogenic Phenotype of Interstitial Cells in Calcified Human Aortic Valves. J Am Heart Assoc. 2017; 6(4). PM ID: 28438736
-
Li, P, et al. (2017) SIRT1 is required for mitochondrial biogenesis reprogramming in hypoxic human pulmonary arteriolar smooth muscle cells. Int. J. Mol. Med.. 2017; 39(5):1127-1136. PM ID: 28339017
-
Lopez, CM. (2017) MiR-34a Regulates the Invasive Capacity of Canine Osteosarcoma Cell Lines. Thesis. 2017;. Link: Thesis
-
Liang, YX, et al. (2016) E2F1 promotes tumor cell invasion and migration through regulating CD147 in prostate cancer. Int. J. Oncol.. 2016; 48(4):1650-8. PM ID: 26891801
-
Li, Q, et al. (2016) Development and Validation of a Rex1-RFP Potency Activity Reporter Assay That Quantifies Stress-Forced Potency Loss in Mouse Embryonic Stem Cells.. Stem Cells Dev.. 2016; 25(4):320-8. PM ID: 26651054
-
Li, Q, et al. (2016) High-Throughput Screens for Embryonic Stem Cells: Stress-Forced Potency-Stemness Loss Enables Toxicological Assays. Protocol. 2016;:1-34. Link: Protocol
-
Lesnik, J, et al. (2016) Registered report: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Elife. 2016; 5:e07383. PM ID: 26826285
-
Irvine, DA, et al. (2016) Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia. Sci Rep. 2016; 6:25476. PM ID: 27157927
-
Chen, Y, et al. (2016) Calcineurin β protects brain after injury by activating the unfolded protein response. Neurobiol. Dis.. 2016; 94:139-56. PM ID: 27334877
-
Tilghman, J, et al. (2016) Regulation of Glioblastoma Tumor-Propagating Cells by the Integrin Partner Tetraspanin CD151. Neoplasia. 2016; 18(3):185-98. PM ID: 26992919
-
Westbroek, W, et al. (2016) A new glucocerebrosidase-deficient neuronal cell model provides a tool to probe pathophysiology and therapeutics for Gaucher disease. Dis Model Mech. 2016; 9(7):769-78. PM ID: 27482815
-
Shrivastava, S, et al. (2016) The Role of HMGB1 in Radioresistance of Bladder Cancer. Mol. Cancer Ther.. 2016; 15(3):471-9. PM ID: 26719575
-
Zhou, A, et al. (2016) RNA Binding Protein HuR Regulates Cardiac Sodium Channel Gene (SCN5A) Expression Through Transcriptional and Post-Transcriptional Pathways. Circulation. 2016; 134(1):A14386. Link: Circulation
- See More