Efficiently pre-clear serum or plasma lipoproteins before exosome isolation
For researchers who specifically want to study exosomal RNA or proteins, removing non-exosomal molecules prior to treatment with ExoQuick® can lead to data that more reliably reports on exosomal RNA or proteins. Because both high density and low density lipoproteins (HDLs and LDLs) can contain miRNAs1, lipoprotein removal is recommended prior to exosome isolation from serum or plasma. ExoQuick-LP® is specifically designed to remove normally-occurring lipoprotein particles from serum or plasma prior to ExoQuick precipitation of exosomes.
The ExoQuick-LP Kit contains ExoQuick and proprietary pre-clearing reagents that efficiently deplete lipoprotein particles from plasma or serum prior to ExoQuick treatment.
Choose the right ExoQuick for your application:
|Purest EV isolation||ExoQuick ULTRA and
|General purpose EV isolation||ExoQuick and
|EV isolation for pre-clinical/in vivo studies||ExoQuick-CG||EXOCG50A-1|
|EV isolation that removes contaminating lipoprotein particles from plasma or serum||ExoQuick-LP||EXOLP5A-1|
|EV isolation that includes a de-fibrinating plasma step prior to isolation||ExoQuick Plasma Prep with Thrombin||EXOQ5TM-1|
- Vickers KC, et al. MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol. 2011 Apr;13(4):423-33.