293TN Producer Cell Line

Overview

Delivering high titer lentivirus preps

Optimized for effective, high-titer production of pseudoviral particles, SBI’s 293TN Producer Cell Line has been transformed with the SV40 large T antigen to promote robust growth and features the neomycin resistance marker for stable propagation. The 293TN packaging cell line is shipped at low passage (P2).

How It Works

Take your transduction efficiencies to a whole new level

Supporting Data

Efficiently package your lentivector with SBI’s 293TN Cells

Figure 1. 293TN cells actively producing lentivirus and packaging a lentivector containing a GFP marker.

Resources

Citations

• Wang, Z, et al. (2019) Nucleophosmin Phosphorylation as a Diagnostic and Therapeutic Target for Ischemic AKI. J. Am. Soc. Nephrol.. 2019 Jan 1; 30(1):50-62. PM ID: 30573638
• He, D, Tan, J & Zhang, J. (2017) miR-137 attenuates Aβ-induced neurotoxicity through inactivation of NF-κB pathway by targeting TNFAIP1 in Neuro2a cells. Biochem. Biophys. Res. Commun.. 2017 Jun 24;. PM ID: 28655611
• Okuda, H, et al. (2017) Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia. J. Clin. Invest.. 2017 May 1; 127(5):1918-1931. PM ID: 28394257
• Han, S, et al. (2017) Expanding the genetic code of Mus musculus. Nat Commun. 2017 Feb 21; 8:14568. PM ID: 28220771
• Oh, IS, et al. (2016) Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner. Exp. Mol. Med.. 2016 Nov 11; 48(11):e270. PM ID: 27833096
• Chang, X, et al. (2016) RIP1 介导肿瘤坏死因子 α 诱导的 L929 细胞凋亡与程序性坏死. 中国细胞生物学学报. 2016 Oct 28; 38(10):1232–1243. Link: 中国细胞生物学学报
• Oki, K, et al. (2016) YPEL4 modulates HAC15 adrenal cell proliferation and is associated with tumor diameter. Mol. Cell. Endocrinol.. 2016 Oct 15; 434:93-8. PM ID: 27333825
• Li, K, et al. (2016) A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors. Cell. 2016 Sep 22; 167(1):60-72.e11. PM ID: 27641503
• Taylor, SE, et al. (2016) Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility. Open Biol. 2016 Sep 1; 6(9). PM ID: 27655733
• Reinisch, A, et al. (2016) A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells. Nat. Med.. 2016 Jul 1; 22(7):812-21. PM ID: 27213817
• Eno, MR, El-Gendy, Bel-D & Cameron, MD. (2016) P450 3A-Catalyzed O-Dealkylation of Lapatinib Induces Mitochondrial Stress and Activates Nrf2. Chem. Res. Toxicol.. 2016 May 16; 29(5):784-96. PM ID: 26958860
• Hsiao, C, et al. (2016) Human pluripotent stem cell culture density modulates YAP signaling. Biotechnol J. 2016 May 1; 11(5):662-75. PM ID: 26766309
• Pereira, SM, et al. (2016) MS-1 magA: Revisiting Its Efficacy as a Reporter Gene for MRI. Mol Imaging. 2016 Apr 27; 15. PM ID: 27118760
• Yeom, SY, et al. (2016) Multiplexed Detection of Epigenetic Markers Using Quantum Dot (QD)-Encoded Hydrogel Microparticles. Anal. Chem.. 2016 Apr 19; 88(8):4259-68. PM ID: 26974493
• Kim, S, et al. (2016) Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration. Oncotarget. 2016 Mar 8; 7(10):11094-112. PM ID: 26848978
• Brayer, KJ, et al. (2016) Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma. Cancer Discov. 2016 Feb 1; 6(2):176-87. PM ID: 26631070
• Welbourn, S & Strebel, K. (2016) Low dNTP levels are necessary but may not be sufficient for lentiviral restriction by SAMHD1. Virology. 2016 Jan 15; 488:271-7. PM ID: 26655245
• Ban, GY, et al. (2016) Autophagy mechanisms in sputum and peripheral blood cells of patients with severe asthma: a new therapeutic target. Clin. Exp. Allergy. 2016 Jan 1; 46(1):48-59. PM ID: 26112695
• Okuda, H, et al. (2015) AF4 uses the SL1 components of RNAP1 machinery to initiate MLL fusion- and AEP-dependent transcription. Nat Commun. 2015 Nov 23; 6:8869. PM ID: 26593443
• Xing, F, et al. (2015) miR-509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF-α. Oncogene. 2015 Sep 10; 34(37):4890-900. PM ID: 25659578