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“S” SARS-CoV-2 Spike Glycoprotein mRNA

Transiently express the SARS-CoV-2 spike glycoprotein (S protein) in the cells of your choice with this ready-to-transfect mRNA.

  • Speed your studies with ready-to-transfect mRNA
  • Transiently express the native (not codon optimized) SARS-CoV-2 spike glycoprotein
  • Stable SARS-CoV-2 spike glycoprotein expression is also available as pre-packaged transduction-ready lentivirus, ready-to-package lentivector, and as a human codon-optimized construct
Catalog Number
Add to Cart
“S” SARS-CoV-2 Spike Glycoprotein mRNA (10 µg, Transfection-ready)
10 µg
$ 345
“S” SARS-CoV-2 Spike Glycoprotein mRNA (20 µg, Transfection-ready)
20 µg
$ 499


Advance your COVID-19 studies with SBI

With transfection-ready “S” SARS-CoV-2 Spike Glycoprotein mRNA, you can easily study infectivity and other interactions of the native SARS-CoV-2 spike glycoprotein from the original Wuhan-1 strain. The “S” SARS-CoV-2 Spike Glycoprotein mRNA delivers robust transient expression to support a range of spike glycoprotein studies.


See all of our COVID-19-related Expression Options

Catalog NumberProduct name
CVD19-100PA/VA-1ACE2 Expression Lentivector, pCDH-CMV-ACE2-EF1α-Puro (Plasmid or Pre-packaged Lentivirus)
CVD19-140PA/VA-1NRP1 Expression Lentivector, pCDH-CMV-NRP1-EF1α-Neo (Plasmid or Pre-packaged Lentivirus)
CVD19-120PA/VA-1SARS-CoV-2 Nucleocapsid (N protein) Expression Lentivector, pCDH-CMV-SARS-CoV-2-N-EF1α-Puro (Plasmid or Pre-packaged Lentivirus)
CVD19-130PA/VA-1SARS-CoV-2 Spike Glycoprotein (S) Expression Lentivector, pCDH-CMV-SARS-CoV-2-S-EF1α-Puro (Plasmid or Pre-packaged Lentivirus)
CVD19-135PA/VA-1SARS-CoV-2 Humanized Spike Glycoprotein (S) Expression Lentivector, pCDH-CMV-SARS-CoV-2-hS-EF1α-Puro (Plasmid or Pre-packaged Lentivirus)
CVD19-200A-1HEK293 ACE2 Stable Cell Line
CVD19-260A-1HEK293-ACE2-NRP1 Overexpression Stable Cell Line
CVD19-220A-1HEK293 "N" SARS-CoV-2 Nucleocapsid Overexpression Stable Cell Line
"N" SARS-CoV-2 Nucleocapsid mRNA
"S" SARS-CoV-2 Spike Glycoprotein mRNA


Supporting Data

“S” SARS-CoV-2 Spike Glycoprotein mRNA is of high-quality

The high quality of the “S” SARS-CoV-2 Spike Glycoprotein mRNA can be seen in Figure 1, which shows that the majority of the in vitro transcribed mRNA migrates as a single species on a 1.5% denaturing agarose gel. A small proportion of the transcript is truncated (indicated by the *) due to an internal sequence in the Spike mRNA that causes T7 polymerase to pause.

Figure 1. The “S” SARS-CoV-2 mRNA is a high-quality mRNA construct that migrates primarily as a single species.

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