Thrombin Plasma Prep
De-fibrinate plasma before exosome isolation for efficient recovery and high yields.
- Chugh PE, et al. Systemically Circulating Viral and Tumor-Derived MicroRNAs in KSHV-Associated Malignancies. PLoS Pathog. 2013. 9(7): e1003484. PMCID: PMC3715412.
Products
| Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
|---|---|---|---|---|---|---|---|---|
| TMEXO-1 | Thrombin Plasma prep for Exosome precipitation (500 µL at 500 U/mL) | 100 Reactions | $541 |
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Overview
Overview
Efficient exosome isolation from plasma
"We therefore pursued the ExoQuick® method for further study, as these samples required much less sample input, a key benefit when working with clinical samples and mouse models1."
When isolating exosomes from plasma, fibrinogen and fibrin can impede efficient recovery. By pre-treating plasma with thrombin, the fibrinogen can be converted to fibrin and easily pre-cleared by a simple centrifugation step. The resulting serum-like solution can now be treated with ExoQuick, original formulation, for quantitative exosome isolation that is compatible with high-throughput methods.
Want to learn more about how ExoQuick works? Find out here.
Choose the right ExoQuick for your application:
| Application | Product | Catalog # |
|---|---|---|
| Purest EV isolation | ExoQuick ULTRA and ExoQuick-TC ULTRA | EQULTRA-20A-1 EQULTRA-20TC-1 |
| General purpose EV isolation | ExoQuick and ExoQuick-TC | EXOQ20A-1 EXOTC50A-1 |
| EV isolation for pre-clinical/in vivo studies | ExoQuick-CG | EXOCG50A-1 |
| EV isolation that removes contaminating lipoprotein particles from plasma or serum | ExoQuick-LP | EXOLP5A-1 |
| EV isolation that includes a de-fibrinating plasma step prior to isolation | ExoQuick Plasma Prep with Thrombin | EXOQ5TM-1 |
REFERENCES
- Chugh PE, et al. Systemically Circulating Viral and Tumor-Derived MicroRNAs in KSHV-Associated Malignancies. PLoS Pathog. 2013. 9(7): e1003484. PMCID: PMC3715412.
References
How It Works
Supporting Data
FAQs
Resources
Citations
Related Products
Products
| Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
|---|---|---|---|---|---|---|---|---|
| TMEXO-1 | Thrombin Plasma prep for Exosome precipitation (500 µL at 500 U/mL) | 100 Reactions | $541 |
|
||||
Overview
Overview
Efficient exosome isolation from plasma
"We therefore pursued the ExoQuick® method for further study, as these samples required much less sample input, a key benefit when working with clinical samples and mouse models1."
When isolating exosomes from plasma, fibrinogen and fibrin can impede efficient recovery. By pre-treating plasma with thrombin, the fibrinogen can be converted to fibrin and easily pre-cleared by a simple centrifugation step. The resulting serum-like solution can now be treated with ExoQuick, original formulation, for quantitative exosome isolation that is compatible with high-throughput methods.
Want to learn more about how ExoQuick works? Find out here.
Choose the right ExoQuick for your application:
| Application | Product | Catalog # |
|---|---|---|
| Purest EV isolation | ExoQuick ULTRA and ExoQuick-TC ULTRA | EQULTRA-20A-1 EQULTRA-20TC-1 |
| General purpose EV isolation | ExoQuick and ExoQuick-TC | EXOQ20A-1 EXOTC50A-1 |
| EV isolation for pre-clinical/in vivo studies | ExoQuick-CG | EXOCG50A-1 |
| EV isolation that removes contaminating lipoprotein particles from plasma or serum | ExoQuick-LP | EXOLP5A-1 |
| EV isolation that includes a de-fibrinating plasma step prior to isolation | ExoQuick Plasma Prep with Thrombin | EXOQ5TM-1 |
REFERENCES
- Chugh PE, et al. Systemically Circulating Viral and Tumor-Derived MicroRNAs in KSHV-Associated Malignancies. PLoS Pathog. 2013. 9(7): e1003484. PMCID: PMC3715412.