XStamp™-CD40L Lentivector for Targeting Exosomes to Antigen-presenting cells
Target exosomes to antigen-presenting cells with the pre-built XStamp-CD40L Lentivector Construct.
- Display CD40L sequences on exosome surfaces
- Target antigen-presenting cells
- Create stable XStamp-CD40L cell lines
Products
Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
---|---|---|---|---|---|---|---|---|
XSTP725PA-1 | XStamp CD40 receptor targeting lentivector - CD40L exosomes target cells with surface CD40 receptor | 10 µg | $787 |
|
Overview
Overview
Putting exosomes to work: Target exosomes to antigen-presenting cells Use exosomes to deliver protein, RNA, DNA, or small molecule cargo to antigen-presenting cells with XStamp-CD40L. The patented XStamp technology is an optimized, exosome surface display system that efficiently places protein sequences on exosomal surfaces. The XStamp-CD40L Lentivector fuses CD40L sequences to the XStamp tag, ensuring that exosomes display the CD40L on their outer surface. Exosomes made from cells transfected or transduced with the XStamp-CD40L Lentivector will now be targeted to cells expressing CD40, primarily antigen-presenting cells.- Display CD40L sequences on exosome surfaces
- Target antigen-presenting cells
- Create stable XStamp-CD40L cell lines
Cat.# | Specificity | Targeting Ligand Used |
---|---|---|
XSTP710PA-1 | Clone-your-own | You decide |
XSTP720PA-1 | GI tract cells | Motilin |
XSTP721PA-1 | Neural cells | NCAM |
XSTP722PA-1 | Brain cells | BHP1 |
XSTP723PA-1 | Cancer cells | GE11 |
XSTP724PA-1 | Breast cancer cells | HER2 |
XSTP725PA-1 | Antigen-presenting cells | CD40L/CD154 |
XSTP726PA-1 | Immune cells | IL-2 |
References
How It Works
How It Works
Engineering exosomes with specific surface proteins
XStamp is based upon a C-terminal fusion of the C1C2 domain from the protein MFG-E8, which is targeted to the exosome surface. Protein sequences that are fused to the XStamp tag will efficiently display the protein ligand fusion on the surfaces of secreted exosomes.
Supporting Data
FAQs
Resources
Citations
Related Products
XStamp™-CD40L Lentivector for Targeting Exosomes to Antigen-presenting cells
$787.00
Products
Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
---|---|---|---|---|---|---|---|---|
XSTP725PA-1 | XStamp CD40 receptor targeting lentivector - CD40L exosomes target cells with surface CD40 receptor | 10 µg | $787 |
|
Overview
Overview
Putting exosomes to work: Target exosomes to antigen-presenting cells Use exosomes to deliver protein, RNA, DNA, or small molecule cargo to antigen-presenting cells with XStamp-CD40L. The patented XStamp technology is an optimized, exosome surface display system that efficiently places protein sequences on exosomal surfaces. The XStamp-CD40L Lentivector fuses CD40L sequences to the XStamp tag, ensuring that exosomes display the CD40L on their outer surface. Exosomes made from cells transfected or transduced with the XStamp-CD40L Lentivector will now be targeted to cells expressing CD40, primarily antigen-presenting cells.- Display CD40L sequences on exosome surfaces
- Target antigen-presenting cells
- Create stable XStamp-CD40L cell lines
Cat.# | Specificity | Targeting Ligand Used |
---|---|---|
XSTP710PA-1 | Clone-your-own | You decide |
XSTP720PA-1 | GI tract cells | Motilin |
XSTP721PA-1 | Neural cells | NCAM |
XSTP722PA-1 | Brain cells | BHP1 |
XSTP723PA-1 | Cancer cells | GE11 |
XSTP724PA-1 | Breast cancer cells | HER2 |
XSTP725PA-1 | Antigen-presenting cells | CD40L/CD154 |
XSTP726PA-1 | Immune cells | IL-2 |
References
How It Works
How It Works
Engineering exosomes with specific surface proteins
XStamp is based upon a C-terminal fusion of the C1C2 domain from the protein MFG-E8, which is targeted to the exosome surface. Protein sequences that are fused to the XStamp tag will efficiently display the protein ligand fusion on the surfaces of secreted exosomes.