XStamp™-HER2 Lentivector for Targeting Exosomes to Breast Cancer Cells
Target exosomes to breast cancer cells with the pre-built XStamp-HER2 Lentivector Construct.
- Display HER2 sequences on exosome surfaces
- Target breast cancer cells
- Create stable XStamp-HER2 cell lines
Products
Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
---|---|---|---|---|---|---|---|---|
XSTP724PA-1 | XStamp Her2 receptor targeting lentivector - Her2 ligand exosomes target cells with surface Her2 receptor | 10 µg | $787 |
|
Overview
Overview
Putting exosomes to work: Target exosomes to breast cancer cells Use exosomes to deliver protein, RNA, DNA, or small molecule cargo to breast cancer cells with XStamp-HER2. The patented XStamp technology is an optimized, exosome surface display system that efficiently places protein sequences on exosomal surfaces. The XStamp-HER2 Lentivector fuses HER2 sequences to the XStamp tag, ensuring that exosomes display the HER2 peptide on their outer surface. Exosomes made from cells transfected or transduced with the XStamp-HER2 Lentivector will now be targeted to cells expressing breast cancer cells.- Display HER2 sequences on exosome surfaces
- Target breast cancer cells
- Create stable XStamp-HER2 cell lines
Cat.# | Specificity | Targeting Ligand Used |
---|---|---|
XSTP710PA-1 | Clone-your-own | You decide |
XSTP720PA-1 | GI tract cells | Motilin |
XSTP721PA-1 | Neural cells | NCAM |
XSTP722PA-1 | Brain cells | BHP1 |
XSTP723PA-1 | Cancer cells | GE11 |
XSTP724PA-1 | Breast cancer cells | HER2 |
XSTP725PA-1 | Antigen-presenting cells | CD40L/CD154 |
XSTP726PA-1 | Immune cells | IL-2 |
References
How It Works
How It Works
Engineering exosomes with specific surface proteins
XStamp is based upon a C-terminal fusion of the C1C2 domain from the protein MFG-E8, which is targeted to the exosome surface. Protein sequences that are fused to the XStamp tag will efficiently display the protein ligand fusion on the surfaces of secreted exosomes.
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Related Products
XStamp™-HER2 Lentivector for Targeting Exosomes to Breast Cancer Cells
$787.00
Products
Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
---|---|---|---|---|---|---|---|---|
XSTP724PA-1 | XStamp Her2 receptor targeting lentivector - Her2 ligand exosomes target cells with surface Her2 receptor | 10 µg | $787 |
|
Overview
Overview
Putting exosomes to work: Target exosomes to breast cancer cells Use exosomes to deliver protein, RNA, DNA, or small molecule cargo to breast cancer cells with XStamp-HER2. The patented XStamp technology is an optimized, exosome surface display system that efficiently places protein sequences on exosomal surfaces. The XStamp-HER2 Lentivector fuses HER2 sequences to the XStamp tag, ensuring that exosomes display the HER2 peptide on their outer surface. Exosomes made from cells transfected or transduced with the XStamp-HER2 Lentivector will now be targeted to cells expressing breast cancer cells.- Display HER2 sequences on exosome surfaces
- Target breast cancer cells
- Create stable XStamp-HER2 cell lines
Cat.# | Specificity | Targeting Ligand Used |
---|---|---|
XSTP710PA-1 | Clone-your-own | You decide |
XSTP720PA-1 | GI tract cells | Motilin |
XSTP721PA-1 | Neural cells | NCAM |
XSTP722PA-1 | Brain cells | BHP1 |
XSTP723PA-1 | Cancer cells | GE11 |
XSTP724PA-1 | Breast cancer cells | HER2 |
XSTP725PA-1 | Antigen-presenting cells | CD40L/CD154 |
XSTP726PA-1 | Immune cells | IL-2 |
References
How It Works
How It Works
Engineering exosomes with specific surface proteins
XStamp is based upon a C-terminal fusion of the C1C2 domain from the protein MFG-E8, which is targeted to the exosome surface. Protein sequences that are fused to the XStamp tag will efficiently display the protein ligand fusion on the surfaces of secreted exosomes.