CUSTOM REPORTER CELL LINE GENERATION

Quickly get your studies up and running—have SBI make custom stable cell lines that have GFP, RFP, or luciferase fusions to promoters and enhancer elements.

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Get greater insights from in vivo studies with reporter-labeled cell lines

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While SBI already offers a number of ready-to-go reporter cell lines, everyone’s studies are different. This is why SBI also offers Custom Reporter Cell Line Generation Services for producing promoter- and/or enhancer-reporter fusions. Save time and effort while leveraging our comprehensive range of technologies and our expert team which has years of experience working with a variety of cell lines, including adherent and suspension cells.

Why choose SBI's Custom Reporter Cell Line Generation Services?

  • Save time by having SBI build your custom cell lines
  • Leverage our highly-regarded gene expression and delivery technologies
  • Accomplish more with our fast turnaround times and end-to-end services
  • Turn to the company that other companies turn to—we are a trusted stable cell line manufacturer for many large pharma/biotech companies
  • Enjoy consistent quality, confidentiality, and on-time delivery with all projects completed on-site in our Palo Alto, CA, facility

Available gene expression and delivery technologies

Viral Systems

  • Lentivectors—high titer and reliable
    • Random integration
    • Limited insert size
    • High copy number
  • Lentivirus Packaging—reliable gene delivery
    • High and ultra-high titers
    • Efficient transduction
    • Optimized reagents

Non-viral Systems

  • PhiC31 Integrase System—one-step single-copy integration
    • Site-specific integration
    • Unlimited insert size
    • Single copy number
  • PinPoint Targeted Integration System—excellent for creating isogenic cell lines
    • Site-specific integration
    • Unlimited insert size
    • Single copy number

SBI’s Stable Cell Line Services are a great way to leverage our highly-regarded lentivector, PhiC31 Integrase, and PinPoint Targeted Integration technologies.

How SBI's Custom Reporter Cell Line Generation Service Works

Step 1

Contact the services team for a quote by emailing services@systembio.com.

Step 2

Send us any necessary materials such as parent cell lines (optional).

Step 3

Receive your stable cell line (turn-around time depends on the complexity of your project).

Supporting Data

Successful generation of dual luciferase and GFP-labeled NF-κB cell line

Figure 1. Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI—monitor and quantitatively measure NFκB transactivation in live cells. Monitor NF-κB activation in real time with GFP using SBI’s NF-κB/293/GFP-Luc™ Transcriptional Reporter Cell Line (Cat.# TR860A-1).

Figure 2. Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI—monitor and quantitatively measure NFκB transactivation in live cells. Quantitatively measure NF-κB activation in real time with luciferase using SBI’s NF-κB/293/GFP-Luc Transcriptional Reporter Cell Line (Cat.# TR860A-1).