Exo-Check™ Exosome Antibody Array
- Sensitive—requires as little as 50 µg of exosomal protein for detection
- Convenient—includes eight antibodies for known exosome markers
- Flexible—compatible with most exosome isolation methods, include the ExoQuick® family of reagents and ultracentrifugation
- Complete—includes a control for cellular contamination, a background control (blank spot), and a labeled positive control for HRP detection
- Semi-quantitative—can be used to evaluate relative abundance of certain exosome markers from a given set of samples
Products
Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
---|---|---|---|---|---|---|---|---|
EXORAY200B-4 | Exo-Check Exosome Antibody Array | 4 Arrays | $498 |
|
||||
EXORAY210B-8 | Exo-Check Exosome Antibody Array | 8 Arrays | $944 |
|
Overview
Overview
Streamline your exosome detection with Exo-Check Arrays
For the most efficient detection of exosomes, turn to our semi-quantitative Exo-Check Exosome Antibody Arrays. Each array has 12 pre-printed spots and features 8 antibodies for known exosome markers (CD63, CD81, ALIX, FLOT1, ICAM1, EpCam, ANXA5 and TSG101), a GM130 cis-Golgi marker to monitor any cellular contamination in your exosome isolations, a labeled positive control for HRP detection, and a blank spot as a background control. The kits come complete with a secondary detection mixture conjugated to HRP.
- Sensitive—requires as little as 50 µg of exosomal protein for detection
- Convenient—includes eight antibodies for known exosome markers
- Flexible—compatible with most exosome isolation methods, include the ExoQuick® family of reagents and ultracentrifugation
- Complete—includes a control for cellular contamination, a background control (blank spot), and a labeled positive control for HRP detection
- Semi-quantitative—can be used to evaluate relative abundance of certain exosome markers from a given set of samples
1 | 2 | 3 | 4 | 5 | 6 | |
---|---|---|---|---|---|---|
A | CD63 | EpCam | ANXA5 | TSG101 | Blank | Positive control |
B | Positive control | GM130 | FLOT-1 | ICAM | ALIX | CD81 |
Spot position* | ID | Notes | Link to ExoCarta entry for the human protein |
---|---|---|---|
A1 | CD63 | Tetraspanin | ExoCarta_967 |
A2 | EpCam | Epithelial cell adhesion molecule; often found in cancer-derived exosomes | ExoCarta_4072 |
A3 | ANXA5 | Annexin A5 | ExoCarta_308 |
A4 | TSG101 | Tumor susceptibility gene 101 | ExoCarta_7251 |
A5 | Blank | Background control | NA |
A6 | Positive control | Positive control for HRP detection (derived from human serum exosomes) | NA |
B1 | Positive control | Labeled positive control for HRP detection | NA |
B2 | GM130 | Cis-golgi matrix protein—control for cellular contamination in exosome preparation | NA |
B3 | FLOT1 | Flotillin-1 | ExoCarta_10211 |
B4 | ICAM1 | Intercellular adhesion molecule 1 | ExoCarta_3383 |
B5 | ALIX | Programmed cell death 6 interacting protein (PDCD6IP) | ExoCarta_10015 |
B6 | CD81 | Tetraspanin | ExoCarta_93185 |
*To correctly orient the array, place the notched corner in the upper left-hand position |
References
How It Works
Supporting Data
FAQs
Related Products
Resources
Citations
-
Zanolla, I, et al. (2024) Adipose-derived stem cell exosomes act as delivery vehicles of microRNAs in a dog model of chronic hepatitis. Nanotheranostics. 2024; 8(3):298-311. Link: Nanotheranostics
-
Coughlan, C, et al. (2024) Specific Binding of Alzheimer’s Aβ Peptides to Extracellular Vesicles. International Journal of Molecular Sciences. 2024; 25(7):3703. Link: International Journal of Molecular Sciences
-
D'mello, R. (2024) Discovery and Validation of Metabolite Biomarkers in Breast Cancer Exosomes Using Liquid Chromatography-Mass Spectrometry. Thesis. 2024;. Link: Thesis
-
García-Gracia, M, et al. (2024) Analysis of Plasma-Derived Exosomal MicroRNAs as Potential Biomarkers for Canine Idiopathic Epilepsy. Animals : an open access journal from MDPI. 2024; 14(2). PM ID: 38254420
-
Holzhausen, E, et al. (2023) Human milk EV-miRNAs: a novel biomarker for air pollution exposure during pregnancy. Environmental Research: Health. 2023;. Link: Environmental Research: Health
-
Honorato-Mauer, J, et al. (2023) Alterations in microRNA of extracellular vesicles associated with major depression, attention-deficit/hyperactivity and anxiety disorders in adolescents. Translational psychiatry. 2023; 13(1):47. PM ID: 36746925
-
Senda, A, et al. (2023) Profiles of lipid, protein and microRNA expression in exosomes derived from intestinal epithelial cells after ischemia-reperfusion injury in a cellular hypoxia model. PloS one. 2023; 18(3):e0283702. PM ID: 36989330
-
Yan, H, et al. (2023) A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs. Nature biomedical engineering. 2023;. PM ID: 37106152
-
Hsu, CC, et al. (2023) Simultaneous Detection of Tumor Derived Exosomal Protein-MicroRNA Pairs with an Exo-PROS Biosensor for Cancer Diagnosis. ACS nano. 2023;. PM ID: 37129374
-
Ahmed, M, et al. (2023) Immune Profile of Exosomes in African American Breast Cancer Patients Is Mediated by Kaiso/THBS1/CD47 Signaling. Cancers. 2023; 15(8):2282. Link: Cancers
-
Dunlop, RA, Banack, SA & Cox, PA. (2023) L1CAM immunocapture generates a unique extracellular vesicle population with a reproducible miRNA fingerprint. RNA biology. 2023; 20(1):140-148. PM ID: 37042019
-
Minic, Z, et al. (2023) Lysine Acetylome of Breast Cancer-Derived Small Extracellular Vesicles Reveals Specific Acetylation Patterns for Metabolic Enzymes. Biomedicines. 2023; 11(4):1076. Link: Biomedicines
-
Mansur, S, et al. (2023) Preparation of Nanoparticle-Loaded Extracellular Vesicles Using Direct Flow Filtration. Pharmaceutics. 2023; 15(5). PM ID: 37242792
-
Meloni, M, et al. (2023) Oligomeric Alpha-Synuclein and STX-1A from Neural-Derived Extracellular Vesicles (NDEVs) as Possible Biomarkers of REM Sleep Behavior Disorder in Parkinson’s Disease: A Preliminary Cohort Study. International journal of molecular sciences. 2023; 24(10). PM ID: 37240185
-
Chu, AJ. (2023) The effects of secreted amyloid precursor protein-alpha on rodent astrocytes and directly reprogrammed human induced neuron-like cells. Thesis. 2023;. Link: Thesis
-
Kang, C, et al. (2023) Harnessing small extracellular vesicles for pro-oxidant delivery: novel approach for drug-sensitive and resistant cancer therapy. Journal of controlled release : official journal of the Controlled Release Society. 2023; 365:286-300. PM ID: 37992875
-
Vitucci, ECM, et al. (2023) Characterizing the extracellular vesicle proteomic landscape of the human airway using in vitro organotypic multi-cellular models. iScience. 2023; 26(11):108162. PM ID: 37920665
-
Carberry, CK, et al. (2023) Extracellular Vesicles altered by a Per- and Polyfluoroalkyl Substance Mixture: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health. Toxicological sciences : an official journal of the Society of Toxicology. 2023;. PM ID: 37851381
-
Richards, T, et al. (2023) Therapeutic Intervention of Neuroinflammatory Alzheimer Disease Model by Inhibition of Classical Complement Pathway with the Use of Anti-C1r Loaded Exosomes. Research square. 2023;. PM ID: 37886595
-
Zhong, T, et al. (2023) Co-Delivery of Bioengineered Exosomes and Oxygen for Treating Critical Limb Ischemia in Diabetic Mice. ACS nano. 2023; 17(24):25157-25174. PM ID: 38063490
- See More
Products
Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
---|---|---|---|---|---|---|---|---|
EXORAY200B-4 | Exo-Check Exosome Antibody Array | 4 Arrays | $498 |
|
||||
EXORAY210B-8 | Exo-Check Exosome Antibody Array | 8 Arrays | $944 |
|
Overview
Overview
Streamline your exosome detection with Exo-Check Arrays
For the most efficient detection of exosomes, turn to our semi-quantitative Exo-Check Exosome Antibody Arrays. Each array has 12 pre-printed spots and features 8 antibodies for known exosome markers (CD63, CD81, ALIX, FLOT1, ICAM1, EpCam, ANXA5 and TSG101), a GM130 cis-Golgi marker to monitor any cellular contamination in your exosome isolations, a labeled positive control for HRP detection, and a blank spot as a background control. The kits come complete with a secondary detection mixture conjugated to HRP.
- Sensitive—requires as little as 50 µg of exosomal protein for detection
- Convenient—includes eight antibodies for known exosome markers
- Flexible—compatible with most exosome isolation methods, include the ExoQuick® family of reagents and ultracentrifugation
- Complete—includes a control for cellular contamination, a background control (blank spot), and a labeled positive control for HRP detection
- Semi-quantitative—can be used to evaluate relative abundance of certain exosome markers from a given set of samples
1 | 2 | 3 | 4 | 5 | 6 | |
---|---|---|---|---|---|---|
A | CD63 | EpCam | ANXA5 | TSG101 | Blank | Positive control |
B | Positive control | GM130 | FLOT-1 | ICAM | ALIX | CD81 |
Spot position* | ID | Notes | Link to ExoCarta entry for the human protein |
---|---|---|---|
A1 | CD63 | Tetraspanin | ExoCarta_967 |
A2 | EpCam | Epithelial cell adhesion molecule; often found in cancer-derived exosomes | ExoCarta_4072 |
A3 | ANXA5 | Annexin A5 | ExoCarta_308 |
A4 | TSG101 | Tumor susceptibility gene 101 | ExoCarta_7251 |
A5 | Blank | Background control | NA |
A6 | Positive control | Positive control for HRP detection (derived from human serum exosomes) | NA |
B1 | Positive control | Labeled positive control for HRP detection | NA |
B2 | GM130 | Cis-golgi matrix protein—control for cellular contamination in exosome preparation | NA |
B3 | FLOT1 | Flotillin-1 | ExoCarta_10211 |
B4 | ICAM1 | Intercellular adhesion molecule 1 | ExoCarta_3383 |
B5 | ALIX | Programmed cell death 6 interacting protein (PDCD6IP) | ExoCarta_10015 |
B6 | CD81 | Tetraspanin | ExoCarta_93185 |
*To correctly orient the array, place the notched corner in the upper left-hand position |
References
How It Works
FAQs
Citations
-
Zanolla, I, et al. (2024) Adipose-derived stem cell exosomes act as delivery vehicles of microRNAs in a dog model of chronic hepatitis. Nanotheranostics. 2024; 8(3):298-311. Link: Nanotheranostics
-
Coughlan, C, et al. (2024) Specific Binding of Alzheimer’s Aβ Peptides to Extracellular Vesicles. International Journal of Molecular Sciences. 2024; 25(7):3703. Link: International Journal of Molecular Sciences
-
D'mello, R. (2024) Discovery and Validation of Metabolite Biomarkers in Breast Cancer Exosomes Using Liquid Chromatography-Mass Spectrometry. Thesis. 2024;. Link: Thesis
-
García-Gracia, M, et al. (2024) Analysis of Plasma-Derived Exosomal MicroRNAs as Potential Biomarkers for Canine Idiopathic Epilepsy. Animals : an open access journal from MDPI. 2024; 14(2). PM ID: 38254420
-
Holzhausen, E, et al. (2023) Human milk EV-miRNAs: a novel biomarker for air pollution exposure during pregnancy. Environmental Research: Health. 2023;. Link: Environmental Research: Health
-
Honorato-Mauer, J, et al. (2023) Alterations in microRNA of extracellular vesicles associated with major depression, attention-deficit/hyperactivity and anxiety disorders in adolescents. Translational psychiatry. 2023; 13(1):47. PM ID: 36746925
-
Senda, A, et al. (2023) Profiles of lipid, protein and microRNA expression in exosomes derived from intestinal epithelial cells after ischemia-reperfusion injury in a cellular hypoxia model. PloS one. 2023; 18(3):e0283702. PM ID: 36989330
-
Yan, H, et al. (2023) A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs. Nature biomedical engineering. 2023;. PM ID: 37106152
-
Hsu, CC, et al. (2023) Simultaneous Detection of Tumor Derived Exosomal Protein-MicroRNA Pairs with an Exo-PROS Biosensor for Cancer Diagnosis. ACS nano. 2023;. PM ID: 37129374
-
Ahmed, M, et al. (2023) Immune Profile of Exosomes in African American Breast Cancer Patients Is Mediated by Kaiso/THBS1/CD47 Signaling. Cancers. 2023; 15(8):2282. Link: Cancers
-
Dunlop, RA, Banack, SA & Cox, PA. (2023) L1CAM immunocapture generates a unique extracellular vesicle population with a reproducible miRNA fingerprint. RNA biology. 2023; 20(1):140-148. PM ID: 37042019
-
Minic, Z, et al. (2023) Lysine Acetylome of Breast Cancer-Derived Small Extracellular Vesicles Reveals Specific Acetylation Patterns for Metabolic Enzymes. Biomedicines. 2023; 11(4):1076. Link: Biomedicines
-
Mansur, S, et al. (2023) Preparation of Nanoparticle-Loaded Extracellular Vesicles Using Direct Flow Filtration. Pharmaceutics. 2023; 15(5). PM ID: 37242792
-
Meloni, M, et al. (2023) Oligomeric Alpha-Synuclein and STX-1A from Neural-Derived Extracellular Vesicles (NDEVs) as Possible Biomarkers of REM Sleep Behavior Disorder in Parkinson’s Disease: A Preliminary Cohort Study. International journal of molecular sciences. 2023; 24(10). PM ID: 37240185
-
Chu, AJ. (2023) The effects of secreted amyloid precursor protein-alpha on rodent astrocytes and directly reprogrammed human induced neuron-like cells. Thesis. 2023;. Link: Thesis
-
Kang, C, et al. (2023) Harnessing small extracellular vesicles for pro-oxidant delivery: novel approach for drug-sensitive and resistant cancer therapy. Journal of controlled release : official journal of the Controlled Release Society. 2023; 365:286-300. PM ID: 37992875
-
Vitucci, ECM, et al. (2023) Characterizing the extracellular vesicle proteomic landscape of the human airway using in vitro organotypic multi-cellular models. iScience. 2023; 26(11):108162. PM ID: 37920665
-
Carberry, CK, et al. (2023) Extracellular Vesicles altered by a Per- and Polyfluoroalkyl Substance Mixture: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health. Toxicological sciences : an official journal of the Society of Toxicology. 2023;. PM ID: 37851381
-
Richards, T, et al. (2023) Therapeutic Intervention of Neuroinflammatory Alzheimer Disease Model by Inhibition of Classical Complement Pathway with the Use of Anti-C1r Loaded Exosomes. Research square. 2023;. PM ID: 37886595
-
Zhong, T, et al. (2023) Co-Delivery of Bioengineered Exosomes and Oxygen for Treating Critical Limb Ischemia in Diabetic Mice. ACS nano. 2023; 17(24):25157-25174. PM ID: 38063490
- See More